Citrulline malate: application to eliminate fatigue

Feeling tired is common to all people. Someone tired of constant training in the pursuit of results and a beautiful body, in others it is a state associated with the clinical symptoms of various diseases. In all these cases, the aid will come with a drug called "Citrulline malate".

What is the substance

Citrulline is an amino acid which is involved in ridding the body of lactic acid and ammonia. These substances and cause muscle fatigue in humans. Citrulline molecule binding to a molecule of an organic salt - malate forming substance citrulline malate. At its core, Malate - is nothing but as malic acid, which the body by means of its processing are used to increase energy.

Citrulline malate transformed to nitric oxide, which enables muscles to consume more glucose and inhibit the accumulation of fatigue. The cell mitochondria, are responsible for energy production, increase in its amount with the increase of nitric oxide. As a result, the muscles begin to contract better, get more blood, which is engaged in the transportation of necessary substances and disposal of waste products.

The most important purpose substances is the ability to increase the production of arginine, which stimulates the growth of nitric oxide. Hence, the focus in the use of the drug for the prevention and removal of excessive fatigue syndrome.

The composition and properties of the drug

The additive consists only of the components in its name. Approximately 55-60% is a citrulline, the remaining 40-45% - malate. To improve the effect of the drug is complemented by various components:

• arginine stimulates the muscles vessels;
• creatine increases muscle mass;
• carnosine, which eliminates the effect on muscle oxidative processes;
• karnetinom, improve heart function;
• vitamin B group and zinc, is the link of all metabolic processes.

The main properties of the substance are:

• to synthesize arginine in the body;
• increase in muscle mass and increased its power;
• increase the energy potential;
• strengthening the immune system;
• maintain normal nitrogen balance;
• improvement in erectile function.

It is possible to say that citrulline malate is a regulator of the set of metabolic processes in the human body and allows it to be not only healthy, but also beautiful.

Application in sport

Recently, in the process of training of athletes using Citrulline Malate. Sports nutrition is used in pre-training complex in power kinds of muscle building. This body building, weight lifting, and fitness t. D. Application of the substance reduces muscle fatigue by improving blood flow. In aerobic exercise (jogging, swimming), the medication helps to strengthen the endurance athlete. The pressure thus remains normal.

In 2015, American scientists have shown that citrulline malate is able to eliminate the protein deficiency in the body without causing hormonal disturbances. Experts advise to use the drug with a very intensive training and high load. To work with one group of muscles of the effect will be negligible.

Application in Medicine

citrulline malate is used for medical purposes in the treatment of the following diseases:

• diabetes;
• metabolic acidosis;
• sleepiness of unknown etiology;
• chronic fatigue syndrome.

The drug is recommended for use in order to speedy recovery after surgery. Also, citrulline malate, reviews which are mostly positive, appointed by the elderly and pregnant women with fatigue.

Medicinal agent belongs to the group of tonic and adaptogens. The most famous drug on the basis of citrulline malate is "Stimol". It is presented in the form of tablets and injectable solution.

Contraindications, except for individual intolerance, have been identified. Of the side effects - a discomfort in the epigastrium at the beginning of reception.

The dosage and especially the use of

Experts recommend daily use citrulline malate, athlete whose appointment is approved by the Ministry of Health. For half an hour before training taken a single dose and 1-2 extra - after waking up and before going to bed. A single additive dosage should be at least 6 g

To enhance the action of the drug are advised to take it before meals, preferably diluted with water in proportions according to the annotations. Before use, it is important to study the composition of additives to comply with the minimum amount of dosage of the drug. Otherwise, the efficiency of reception will be insignificant.

In the medical purposes for adults and children recommended citrulline malate. How to accept - is painted in preparation instructions. Typically, for adult use is limited to a single dose of 200 mg and a frequency of reception from 1 to 3 times a day. The course of treatment should not exceed 12 days. Children under 5 years of registered receiving 200 mg once daily. From 5 to 15 years - 400 mg in 2 divided doses. In use, the drug must exercise caution if the patient is on a diet without salt, m. K. The medicament comprises sodium.

Natural substitutes citrulline

The greatest amount of citrulline malate contained in watermelon. Studies using this particular berries and led to the study of amino acids as an energy means increased content of which is also characterized by:

• beans;
• fish;
• meat;
• milk;
• the onion and garlic.

Beans is the source of citrulline plant. The watermelon is especially a lot of the substance in the peels and seeds.

Use of citrulline malate in sports, and for medicinal purposes has a positive effect on the organism as a whole: thus relieving the symptoms of fatigue and achieve excellent athletic performance, while strengthening the immune system.